Los Osos is an unincorporated community located along the Pacific coast of western San Luis Obispo County, California. The community is combined with Baywood Park to form the Census Designated Place of Baywood-Los Osos.
Los Osos is largely a bedroom community for San Luis Obispo, which is 10.6 miles east, and to a lesser extent, Morro Bay, which is 2.3 miles to the north. There is a small business district concentrated in just a few blocks along Los Osos Valley Road, and several shops servicing the Baywood section of Loso Osos, near the bay. The rest of the town is almost entirely residential.
There are two roads connecting Los Osos to other communities: South Bay Boulevard, which leads to Morro Bay via Highway 1, and Los Osos Valley Road, which leads to San Luis Obispo. Inclement weather and road construction occasionally forces the closure of a route, possibly requiring detours to arrive at one's destination. This has been much less frequent since the Chorro Bridge replaced the Twin Bridges on South Bay Boulevard.
Los Osos serves as the entrance to Montaña de Oro State Park. Los Osos Valley Road reaches the coast at the south end of Estero Bay and continues south into the state park. Morro Bay State Park borders the northeast of the town. South Bay Boulevard travels through the middle of the park after it leaves Los Osos.
Large groves of non-native eucalyptus trees attract the annually migrating Monarch butterflies to Los Osos.