This region has many globally known places and geographical features including Torres del Paine, Cape Horn, Tierra del Fuego island, and the Strait of Magellan. It also includes the Antarctic territory claimed by Chile.

The low population and vastness makes this region a good place for many native animal and plant species. It is relatively easy to find penguins, nandus, guanacos, condors, and other animals in their natural environment.

The main economic activities are bovine farming, oil extraction and tourism. This region is also home to an adventure race nown as the Patagonia Expedition Race.